学術研究データベース - 青柳裕

アオヤギ　ユタカ AOYAGI Yutaka
青柳裕

所属金城学院大学薬学部薬学科

金城学院大学大学院薬学研究科薬学専攻

職種教授

著書・論文歴
著書	薬がわかる構造式集 (共著) 2013/12
著書	第7版日本薬局方要説 (共著) 2012/02
著書	第6版日本薬局方要説 (共著) 2010/02
著書	CBT対策と演習～有機化学 (共著) 2008/03
論文	Structures of bicyclic hexapeptides RA-XXVII and RA-XXVIII from Rubia cordifolia L. 147,155190 (共著) 2024/07/15
論文	Kamebakaurin Suppresses Antigen-Induced Mast Cell Activation by Inhibition of FcεRI Signaling Pathway International Archives of Allergy and Immunology 185 (9),836-847頁 (共著) 2024/05/24
論文	化学実習と薬理学実習の連携を目指した、学生が合成した化合物の薬理活性の評価～気管支喘息治療薬テオフィリンの合成と気管平滑筋弛緩作用～ 20 (2),1-6頁 (共著) 2024/03
論文	Synthesis of 1-O-acyl- and 1-oxo-kamebanin analogues and their cytotoxic activity Bioorganic & Medicinal Chemistry Letters 82,129149 (共著) 2023/01/21
論文	Semisynthesis of Antitrypanosomal p-Quinone Analog Possesing the Komaroviquinone Pharmacophore Chem. Pharm. Bull. 70 (4),300-303頁 (共著) 2022/04/01
論文	Potential anti-allergic effects of bibenzyl derivatives from liveworts, Radula perrottetii Planta Medica 88 (12),1069-1077頁 (共著) 2022/03/30
論文	Lipase TL®-mediated kinetic resolution of glycerol analogues: Efficient convergent route to both enantiomeric glycerol units Tetrahedron Lett. 2021, 153138 73 (共著) 2021/04/29
論文	Garcinielliptone G from Garcinia subelliptica induces apoptosis in acute leukemia cells Molecules 26,2422 (共著) 2021/04/21
論文	Effects of ent-kaurene diterpenes from Rabdosia excisa on cardiac function of guinea pigs 名古屋学院大学論集（人文・自然科学篇）2021 57,19-27頁 (共著) 2021/01/31
論文	Five New Highly Oxidized Neoclerodane Diterpenes, Salvileucalins E-I from Salvia leucantha Heterocycles 100 (12),2061-2071頁 (共著) 2020/10/15
論文	Semisynthesis of triptolide analogues part IV: effects of C-14　carbamothioate substituents on cytotoxic activities Heterocycles, 2019 98,977-983頁 (共著) 2019/09
論文	薬物性光線過敏症と紫外線可視吸収スペクトルと構造の関連医薬品情報学, 2019 21,70-78頁 (共著) 2019/09
論文	Protection from acetaminophen-induced hepatotoxicity by post-administration of 1O,20O-diacetyl kamebakaurin in mice Fundamental Toxicological Sciences, 2018 5,161-165頁 (共著) 2018/11
論文	1O, 20O-diacetylkamebakaurin protects against acetaminophen-induced hepatotoxicity in mice Biomedical Research, 2018 39,251-260頁 (共著) 2018/10
論文	薬学部生のキャリアに対する意識調査ー女子学生が考えるキャリアとはー薬学教育, 2018 2,2018-2028頁 (共著) 2018/10
論文	methyl dehydroabiatate counters high fat diet-induced insulin resistance and hepatic steatosis by modulating peroxisome proliferator-activated receptor signaling in mice Biomedicine & Pharmacotherapy2018 99,214-219頁 (共著) 2018/02
論文	Suppressive effect of kamebakaurin on acetaminophen-induced hepatotoxicity by inhibitiog lipid peroxidation and inflammatory responce in mice Pharmacological Reports (共著) 2017/04
論文	図書館有効利用の一事例－金城学院大学薬学部における屋根瓦方式PBLチュートリアル教育－ (共著) 2016/02
論文	Efficient transformation of 7,14-dihydroxy-ent-kaurenes to novel ent-abietanes having cis-fused alfa-methylene gamma-lactones under Mitsunobu reaction conditions and their cytotoxicities (共著) 2014/03
論文	Semisynthesis of Salviandulin E analogues and their Antitrypanosomal Activity Bioorg. Med. Chem. Lett. (共著) 2014/01
論文	Absolute Structures of Stemona-lactam S and　Tuberostemospiroline,　Alkaloids from Stemona tuberosa Chem. Pharm. Bull. (共著) 2013/10
論文	Conformational folding of mycobacterial methoxy- and ketomycolic acids facilitated by alfa-methyl trans-cyclopropane groups rather than cis-cyclopropane units Microbiology (共著) 2013/09
論文	Abietane Diterpenoids and a Sesquiterpene Pyridine Alkaloid from　Euonymus lutchuensis J. Nat. Prod. (共著) 2013/06
論文	Semisynthesis of Triptolide Analogues: Effect of gamma-lactone and C-14 Substituents on Cytotoxic Activities Bioorg. Med. Chem. Lett. 21,3046-3049頁 (共著) 2011/03
論文	Synthesis of Rabdokunmin C Analogues and their Inhibitory Effect on NF-kappaB Activation Bioorg. Med. Chem. Lett 19,2450-2457頁 (共著) 2011/03
論文	Salvileucalin C, a Novel Rearranged Neoclerodane Diterpene from Salvia leucantha Tetrahedron Lett 52,1851-1853頁 (共著) 2011/02
論文	Differential Conformational Behaviors of alfa-Mycolic Acids in Langmuir Monolayers and Computer Simulations Chem. Phys. Lipids 163,569-579頁 (共著) 2010/03
論文	Cytotoxic Bisnor- and Norditerpene Dilactones Having 7alfa, 8alfa- Epoxy-9,11-enolide Substructure from Podocarpus macrophyllus D. Don Chem. Pharm. Bull 57,668-679頁 (共著) 2009/07
論文	First Asymmetric Synthesis of CJ-14877 and its Enantiomer and their Interleukin-1beta Inhibitorty Activities Bioorg. Med. Chem. Lett 19,1876-1878頁 (共著) 2009/02
論文	New Cytotoxic Nor- and Bisnorditerpene Dilactones, Makilactones A-D, from Podocarpus Macrophyllus D. Don Heterocycles 78,1453-1462頁 (共著) 2009/01
論文	Antibacterial Novel Phenolic Diterpenes from the Bark of Podo- carpus Macrophyllus D. Don. Chem. Pharm. Bull 56,1691-1697頁 (共著) 2008/09
論文	Salvileucalins B, A Novel Diterpenoid with an Unprecedented Rearranged Neoclerodane Skeleton from Salvia leucantha Cav. Org. Lett 10,4429-4432頁 (共著) 2008/09
論文	Efficient Synthesis of 2-Mono and 2,3-Disubstituted Indoles via Palladium-Catalyzed Oxidation of Amino alcohols Bioorg. Med. Chem 18,2459-2463頁 (共著) 2008/02
論文	Fluorination of Triptolide and its Analogues with their Cytotoxicity Bioorg. Med. Chem 18,2459-2463頁 (共著) 2008/02
論文	Conformational Behavior of Oxygenated Mycobacterial Mycolic Acids from Mycobacterium bovis BCG Biochim. Biophys. Acta 1768,1717-1726頁 (共著) 2007/04
論文	Tricalysiamide A-D, Diterpenoid Alkaloids from Tricalysia dubia J. Nat. Prod 70,758-762頁 (共著) 2007/04
論文	Three New Diterpenoids, Tricalysiolide H and Tricalysiones A and B, from Tricalysia dubia Tetrahedron 63,4558-4562頁 (共著) 2007/03
論文	Tricalysiolides A-F, New Rearranged ent-Kaurene Diterpenes, from Tricalysia dubia Tetrahedron 62,1512-1519頁 (共著) 2006/12
論文	Semisynthesis of Isetexane Diterpenoid Analogues and their Cytotoxic Activity Chem. Pharm. Bull 54,1602-1604頁 (共著) 2006/11
論文	Efficient Synthesis of Pyrroles and 4,5,6,7-Tetrahydroindoles via Palladium-Catalyzed Oxidation of Hydroxy-Enamines Tetrahedron 62,8533-8538頁 (共著) 2006/07
論文	Synthesis of 1O- or 12O- Mono- and 1O,12O-Diacylexcisanin A 7,14-acetonides and their Cytotoxic Activity Bioorg. Med. Chem 14,5802-5811頁 (共著) 2006/07
論文	Cytotoxity of Abietane Diterpe-noids from Perovskia Abrotanoides and their Semisynthetic Analogues Bioorg. Med. Chem 14,5285-5291頁 (共著) 2006/04
論文	Semisynthesis of C-Ring Modified Triptolide Analogues and their Cytotoxic Activities Bioorg. Med. Chem 16,1947-1949頁 (共著) 2006/02
論文	Biomimetic Synthesis of Gran- dione from Demethylsalvicanol via Hetero Diels-Alder Type Dimerization and Structure Revision of Grandione Tetrahedron Lett 46,7885-7887頁 (共著) 2005/10
論文	Asymmetric Synthesis of (2R,3R,4R)-3-Hydroxy-4-methylprrolidine via Chromium(II) Chloride- Mediated Coupling Reactions of (S)-Garner Aldehyde with Crotyl Bromide Heterocycles 65,2657-2665頁 (共著) 2005/09
論文	The Isolation and Structure Elucidation of a New Sesquiterpene Lactone from a Poisonous Plant Coriaria japonica (Coriariaceae) Chem. Pharm. Bull 53,1040-1042頁 (共著) 2005/08
論文	New Cytotoxic Norditerpene Dilactones from Leaves of Podocarpus macrophyllus var. maki Heterocycles 63,347-357頁 (共著) 2004/12
論文	Efficient Synthesis of novel cytotoxic cis-fused alfa-methylene gamma-lactones from 7,14-Dihydroxy-ent-Kaurenes by Transformation under Mitsunobu Reaction Conditions: Synthsis of Novel Cytotoxic cis-Fused alfa-Methylene gamma-Lactone Tetrahedron Lett 45,1421-1425頁 (共著) 2004/02
論文	Excisanin H, a Novel Cytotoxic 14, 20-Epoxy-ent-kaurene Diterpenoid, and Three New ent-Kaurene Diterpenoids from Rabdosia excisa J. Nat. Prod 67,373-376頁 (共著) 2004/02
論文	Rakanmakilactones A-F, New Cytotoxic Sulfur-Containing Norditerpene Dilactones from Leaves of Podocarpus macrophyllus var. maki Tetrahedron 60,171-177頁 (共著) 2004/01
論文	Lipase TL^®-Mediated Kinetic Resolution of 5-Benzyloxy-1-tert-butyldimethylsilyloxy-2-pentanol at Low Temperature: Concise Asymmetric Synthesis of Both Enantiomers of a Piperazic Acid Derivative J. Org. Chem 68,6899-6904頁 (共著) 2003/08
論文	SR-Podolactone D, a New Sulfoxide Containing Norditerpene Dilactone from Podocarpus macrophyllus var. maki J. Nat. Prod 66,282-284頁 (共著) 2003/01
論文	Location of Functional Groups in Mycobacterial Meromycolate Chains; the Recognition of New Structural Princeples in Mycolic Acids Microbiology 148,1881-1902頁 (共著) 2002/02
論文	Asymmetric synthesis of [2,3-¹³C₂,¹⁵N]-4-Ben zyloxy-5,6- diphenyl-2,3,5,6-tetrahydro-4H-oxazine-2-one via Lipase TL-Mediated Kinetic Resolution of Benzoin: General Procedure for the Synthesis of [2,3-¹³C₂,¹⁵N]-L-Alanine J. Org. Chem 66,8010-8014頁 (共著) 2001/10
論文	Effect of Alkylpyrazine Deriva- tives on the Duration of Pentobar- bital-Induced Sleep, Picrotoxicin- Induced Convulsion and gamma-Aminobutyric Acid (GABA) Levels in the Mouse Brain Biol. Pharm. Bull 24,1068-1071頁 (共著) 2001/09
論文	Separation and Characterization of Individual Mycolic Acids in Representative Mycobacteria Microbiology 147,1825-1837頁 (共著) 2001/04
論文	Stereocontrolled Asymmetric Synthesis of alfa-Hydroxy-beta-Amino Acids. A Stereodivergent Approach J. Am. Chem. Soc 123,3472-3477頁 (共著) 2001/03
論文	Lipase TL<sus>®</sus>-Mediated Kinetic Resolution of Benzoin: Facile Synthesis of (1R,2S)-erythro-2-Amino-1,2-diphenylethanol Tetrahedron Lett 41,10159-10162頁 (共著) 2000/11
論文	Syntheses of Biologically Active Natural Products Using Metal- Mediated Reactions as Key Reactions Yakugaku Zasshi 120,1035-1050頁 (共著) 2000/10
論文	Pharmacological Effects of Urinary Products Obtained after Treatment with Saiboku-To, a Herbal Medicine for Bronchial Asthma, on Type IV Allergic Reaction Planta Med 66,607-611頁 (共著) 2000/03
論文	Asymmetric Synthesis of 1-Boc-3- and 4-Hydroxypyrrolidines Tetrahedron 54,13045-13058頁 (共著) 1998/11
論文	Chromium(II) Chloride-Mediated Coupling Reactions of Garner Aldehydes with Allyl Bromides: Facile Asymmetric Synthesis of (2R,3S)-3- Hydroxy-2-hydroxymethylpyrrolidine J. Chem. Soc. Perkin Trans 1,3975-3978頁 (共著) 1998/11
論文	Efficient Asymmetric Synthesis of (S)-2-Methylasparagine Synlett,1099-1101頁 (共著) 1998/10
論文	General Asymmetric Synthesis of Hydroxymethylene and Hydroxyethylene Peptide Isosteres Tetrahedron 54,10419-10433頁 (共著) 1998/10
論文	The Chemistry of Pyrazines Reviews on Heteroatom Chem 18,141-167頁 (共著) 1998/01
論文	Anti-Platelet Aggregation Activity of Some Pyrazines Biol. Pharm. Bull 20,1076-1081頁 (共著) 1997/10
論文	Facile and Efficient Deoxygenation of Aromatic N-Oxides with Zinc and Aqueous Ammonium Chloride Synthesis,891-894頁 (共著) 1997/08
論文	Total Synthesis of (-)-Bulgecinine Chem. Pharm. Bull 45,962-965頁 (共著) 1997/06
論文	Structures of Phenolic Glyco-lipids from Mycobacterium Kansasii Eur. J. Biochem 248,93-98頁 (共著) 1997/05
論文	Reactions of Pyrazines, Syntheses of Pyrazines Yakugaku Zasshi 117,1-17頁 (共著) 1997/01
論文	Syntheses of Naturally Occurring Pyrazines Yakugaku Zasshi 117,32-48頁 (共著) 1997/01
論文	Facile and Efficient Synthesis of Pyrroles and Indoles via Palladium- Catalyzed Oxidation of Hydroxy-Enamines and Amines Tetrahedron 37,9203-9206頁 (共著) 1996/11
論文	Samarium(II) Iodide-Mediated Intermolecular Coupling Reactions of N, N-Dibenzylenamides with Carbonyl Compounds and Transformation of the Product, N,N-Dibenzyl-gamma-hydroxyamide to delta-Aminoalcohol Chem. Pharm. Bull 44,1812-1818頁 (共著) 1996/10
論文	Samarium(II) Iodide-Mediated Intermolecular Coupling Reactions of N, N-Dibenzyl-alfa-haloamides with Carbonyl Compounds Synthesis,970-974頁 (共著) 1996/08
論文	First Total Synthesis of Pyrrolam A Tetrahedron 52,869-876頁 (共著) 1996/02
論文	Synthesis of Egonol and (±)-Machicendiol Heterocycles 41,1077-1084頁 (共著) 1995/05
論文	Stereoselective 1,4-Dipolar Cycloadditions of 2-(Methylthio)- 3,6-dihydro-3,5-dimethyl-6-oxo-1-substituted Pyrimidine-4-olates with Alkene Chem. Pharm. Bull 43,705-707頁 (共著) 1995/04
論文	Samariumu(II) Diiodide-Mediated Intermolecular Aldol Type Reactions of Phenacyl Bromides with Carbonyl Compounds J. Chem. Soc. Perkin Trans 1,689-692頁 (共著) 1995/01
論文	First total synthesis of (±)-oxerine Tetrahedron 50,13575-13582頁 (共著) 1994/12
論文	Low-Valent Tantalum-Mediated Reaction J. Chem. Soc., Chem. Commum,1225-1226頁 (共著) 1994/04
論文	First Total Synthesis of Astechrome: Novel Hydroxamic Acid with an Indolepyrazine Skeleton Chem. Pharm. Bull 42,277-279頁 (共著) 1994/02
論文	Approach to the Synthesis of Astechrome Heterocycles 35,1279-1287頁 (共著) 1993/02
論文	The Chemistry of Pyrazines. Syntheses of Naturally Occurring Pyrazines Trends in Heterocyclic Chemistry 3,211-233頁 (共著) 1993/01
論文	Synthesis of OPC-15161 Heterocycles 34,1847-1856頁 (共著) 1992/09
論文	Palladium-Catalyzed Cross-Coupling Reactions of Chloro-pyrazines with Aromatic Heterocycles Heterocycles 33,257-272頁 (共著) 1992/01
論文	Synthesis of 2-(Indol-3-yl)mthyl- 5-methylpyrazins, the Skeleton of Astechrome Heterocycles 34,111-119頁 (共著) 1992/01
論文	Synthesis of Halohydroxy-pyrazines and their Synthetic Utitility Heterocycles 32,2407-2415頁 (共著) 1991/12
論文	First Synthesis of (+)-Septorine Heterocycles, 923-93 32 (共著) 1991/05
論文	Effects of the Mammalian Lignan 2,3-Dibenzylbutane-1,4-diol, on Cont- raction and Ca²⁺ Mobiliza tion Induced by Noradrenaline in Rat Aorta Gen. Pharmac 22,663-668頁 (共著) 1991/04
論文	Efficient Alkylation and Acylation of Pyrazine 1-Oxides Heterocycles 32,735-748頁 (共著) 1991/04
論文	Palladium-Catalyzed Arylation of Furan, Thiophene, Benzo[b]furan, and Benzo[b]thiophene Heterocycles 31,1951-1958頁 (共著) 1990/11
論文	Emeheterone: Synthesis and Structural Revision Heterocycles 31,1655-1662頁 (共著) 1990/09
論文	Synthesis of Argvalin and its Related Compound Heterocycles 27,437-444頁 (共著) 1988/02
論文	Synthesis of Arglecin Heterocycles 26,3181-3191頁 (共著) 1987/12