学術研究データベース - 佐伯憲一

サエキ　ケンイチ SAEKI Kenichi
佐伯憲一

所属金城学院大学薬学部薬学科

職種教授

著書・論文歴
著書	衛生試験法・注解2020 (共著) 2020/03
著書	衛生試験法・注解2015 (共著) 2015/03
著書	第96回　薬剤師国家試験 -新国家試験形式　解答・解説集- 2011 (共著) 2011/06
著書	横浜薬科大学衛生系実習・実習書 (共著) 2010/09
論文	Protective effect of Actinidia arguta in MPTP-induced Parkinson’s disease model mice Biochemical and Biophysical Research Communications (共著) 2021/05
論文	Phenotypic analysis of human CYP2C9 polymorphisms using fluorine-substituted tolbutamide Drug Discoveries & Therapeutics 14 (共著) 2020/08
論文	Hepatocarcinogen 4-methylquinoline induced G:C to C:G transversions in T the cII gene in the liver of lambda/lacZ transgenic mice (MutaTMMouse) Mutation Research 821,161-166頁 (共著) 2020/05
論文	薬学部生のキャリアに対する意識調査ー女子学生が考えるキャリアとはー薬学教育（2018） 2 (共著) 2018/10
論文	横浜薬科大学における実務実習事前学習の進捗状況薬剤師会会誌 124,23-25頁 (共著) 2010/07
論文	横浜薬科大学第一期生の実務実習に向けての意識薬剤師会会誌 124,26-29頁 (共著) 2010/07
論文	幼児の突発性発疹による高熱・発疹に井穴刺絡が有効であった症例日本刺絡学会誌（Journal of the Japan Association of Shiraku Acupuncture） 13 (1),36-38頁 (共著) 2010/04
論文	Radiation Dose-Rate Effect on Mutation Induction in Spleen and Liver of gpt delta Mice Radiation Research 173 (2),138-147頁 (共著) 2010/02
論文	Clastogenicity of quinoline derivatives in the liver micronucleus assay using rats and mice Journal of Health Science 53 (4),470-474頁 (共著) 2007/08
論文	Clastogenicity of quinoline and monofluorinated quinolines in chinese hamster lung cells Journal of Health Science 53 (3),325-328頁 (共著) 2007/06
論文	Modification of mutagenicity by fluorine-substitution on diazachrysene Journal of Health Science 53 (3),320-324頁 (共著) 2007/06
論文	Phenotype analysis of human CYP2C9 polymorphism using a panel of fluorine-substituted benzo[h]quinolines as inhibitors of tolbutamide hydroxylation Journal of Health Science 52 (6),821-824頁 (共著) 2006/12
論文	CYP2E1/2A6-Selective inhibition by halogenated anilines on metabolic activation of dimethylnitrosamine in human liver microsomes Journal of Health Science 52 (5),87-95頁 (共著) 2006/10
論文	Nitrogen-substitution effect on in vivo mutagenicity of chrysene Mutation Research 586 (1),1-17頁 (共著) 2005/09
論文	Nitrogen-substitution effects on the mutagenicity and cytochrome P450 isoform-selectivity of chrysene analogs Mutation Research 586 (1),87-95頁 (共著) 2005/09
論文	Inhibition of human cytochrome P450 2E1 by halogenated anilines, phenols, and thiophenols Biological＆Pharmaceutical Bulletin 28 (7),1221-1223頁 (共著) 2005/07
論文	Aryl hydrocarbon receptor-mediated induction of microsomal drug-metabolizing enzyme activity by indirubin and indigo Biochemical and Biophysical Research Communications 318 (2),571-578頁 (共著) 2004/05
論文	In vivo mutagenicity of benzo[f]quinoline, benzo[h]quinoline, and 1,7-phenanthroline using the lacZ transgenic mice Mutation Research 559 (1-2),83-95頁 (共著) 2004/04
論文	Metabolic activation of 10-aza-substituted benzo[a]pyrene by cytochrome P450 1A2 in human liver microsomes Mutation Research 557 (2),159-165頁 (共著) 2004/02
論文	Activation of the human Ah receptor by aza-polycyclic aromatic hydrocarbons and their halogenated derivatives Biological＆Pharmaceutical Bulletin 26 (4),448-452頁 (共著) 2003/04
論文	Effect of 10-aza-substitution on benzo[a]pyrene mutagenicity in vivo and in vitro Mutation Research 521 (1-2),187-200頁 (共著) 2002/12
論文	Study of in vitro glucuronidation of hydroxyquinolines with bovine liver microsomes Fundamental＆ Clinical Pharmacology 16 (6),513-517頁 (共著) 2002/12
論文	Activation of the aryl hydrocarbon receptor by methyl yellow and related congeners: structure-activity relationships in halogenated derivatives Biological＆Pharmaceutical Bulletin 25 (4),466-471頁 (共著) 2002/04
論文	The influence of quinoline on coumarin 7-hydroxylation in bovine liver microsomes and human CYP2A6 Journal of Health Science 48 (2),173-182頁 (共著) 2002/04
論文	Indirubin and Indigo are potent aryl hydrocarbon receptor ligands present in human urine The Journal of Biological Chemistry 276 (34),31475-31478頁 (共著) 2001/08
論文	含窒素芳香族化合物のフッ素置換による抗発癌性構造修飾 YAKUGAKU ZASSHI 120 (12),1373-1385頁 (単著) 2000/12
論文	Hepatocarcinogen quinoline induces G:C to C:G transversions in the cII gene in the liver of lambda/lacZ transgenic mice (MutaTMMouse) Mutation Research 456 (1-2),73-81頁 (共著) 2000/11
論文	Anti-mutagenic structural modification by fluorine-substitution in highly mutagenic 4-methylquinoline derivatives Mutation Research 465 (1-2),173-182頁 (共著) 2000/02
論文	Clastgenicity of quinoline derivatives tested by micronucleus induction in vivo in the hepatocytes of partially hepatectmized mice Biological＆Pharmaceutical Bulletin 23 (2),219-221頁 (共著) 2000/02
論文	Mutagenicity of 4-nitroquinoline 1-oxide in the MutaTMMouse Mutation Research 444 (2),321-336頁 (共著) 1999/08
論文	Substituent effect of a fluorine atom on the mutagenicity of nitroquinolines Mutation Research 441 (2),205-213頁 (共著) 1999/05
論文	Effects of oligofluorine substitution on the mutagenicity of quinoline: a study with twelve fluoroquinoline derivatives Mutation Research 439 (2),149-157頁 (共著) 1999/02
論文	Antimutagenic structual modification of quinoline assessed by an in vivo lacZ-transgenic mice Mutation Research 414 (1-3),165-169頁 (共著) 1998/05
論文	In vivo mutagenesis by the hepatocarcinogen quinoline in the lacZ transgenic mouse: Evidence for its in vivo genotoxicity Mutation Research 412 (2),161-166頁 (共著) 1998/01
論文	Dual stimulatory and inhibitory effects of fluorine-substitution on mutagenicity: An extension of the enamine epoxide theory for activation of the quinoline nucleus Biological＆Pharmaceutical Bulletin 20 (6),646-650頁 (共著) 1997/06
論文	Modification of the carcinogenic potency of quinoline, a hepatocarcinogen, by fluorine atom substitution: Evaluation of carcinogenicity by a medium-term assay Biological＆Pharmaceutical Bulletin 20 (1),40-43頁 (共著) 1997/01
論文	Substituent effect of an N-amino group on the H-D exchange of ring hydrogens of adenines compared with an N-methyl group Heterocycles 45 (1),157-162頁 (共著) 1997/01
論文	Fluorinated benzo[h]quinolines and benzo[f]quinolines Chemical＆Pharmaceutical Bulletin 44 (12),2254-2258頁 (共著) 1996/12
論文	Organ variation in the mutagenicity of ethylnitrosourea in MutaTMMouse: Results of the collaborative study on the transgenic mutation assay by JEMS/MMS Environmental and Molecular Mutagenesis 28,363-375頁 (共著) 1996/12
論文	Hydrogen-exchange reaction of methyl-substituted N-amino- and N-methyl-quinolinium ions Heterocycles 43 (9),1951-1958頁 (共著) 1996/09
論文	Substituent effect of the fluorine atom on electrophilic deuteration of benzo[h]quinoline Heterocycles 43 (9),1937-1942頁 (共著) 1996/09
論文	Potent mutagenic potential of 4-methylquinoline: Metabolic and mechanistic considerations Biological＆Pharmaceutical Bulletin 19 (4),541-546頁 (共著) 1996/04
論文	Effect of fluorine-substitution on basicity of benzo[h]quinoline and benzo[f]quinoline and quinoline Heterocycles 41 (2),315-322頁 (共著) 1995/02
論文	フッ素置換アミノキノリン類の変異原性－その代謝活性化機構の考察－変異原性試験 2 (4),234-238頁 (共著) 1993/10
論文	Metabolism of Mutagenicity-Deprived 3-Fluoroquinoline: Comparison with Mutagenic Quinoline Biological＆Pharmaceutical Bulletin 16 (3),232-234頁 (共著) 1993/03
論文	Spin-Spin Coupling between Fluorine and Aromatic Protons of 3-Fluoroquinoline: Dependence on the Electronic Structure of the Ring Nitrogen Heterocycles 33 (1),35-38頁 (共著) 1992/01