学術研究データベース
閉じる
フクイシ ノブユキ
FUKUISHI Nobuyuki
福石 信之
所属
金城学院大学 薬学部 薬学科
金城学院大学大学院 薬学研究科 薬学専攻
職種
教授
著書・論文歴
著書
パートナー薬理学 改訂第4版 (共著) 2024/03
著書
図解 薬害・副作用学 改訂3版 (共著) 2023/04/01
論文
Kamebakaurin Suppresses Antigen-Induced Mast Cell Activation by Inhibition of FcεRI Signaling Pathway Int Arch Allergy Immunol. 24,1-12頁 (共著) 2024/01
論文
Difference in the Inhibitory Effect of Thiol Compounds and Demetallation Rates from the Zn(II) Active Site of Metallo-β-lactamases (IMP-1 and IMP-6) Associated with a Single Amino Acid Substitution. ACS Infect Dis. 13 (9),65-78頁 (共著) 2023/01
論文
A Rapid and Sensitive Determination of Histamine in Mast Cells Using a Didansyl Derivatization Method. Int Arch Allergy Immunol. 8,1-6頁 (共著) 2022/07
論文
Potential Anti-allergic Effects of Bibenzyl Derivatives from Liverworts,
Radula perrottetii
. Planta Med. 88 (12),1069-1077頁 (共著) 2022/01/26
論文
Nonenzymatic Deamidation Mechanism on a Glutamine Residue with a C-Terminal Adjacent Glycine Residue: A Computational Mechanistic Study AppliedChem 1 (2),142-155頁 (共著) 2021/12
論文
Crystal Structures of Metallo-β-Lactamase (IMP-1) and Its D120E Mutant in Complexes with Citrate and the Inhibitory Effect of the Benzyl Group in Citrate Monobenzyl Ester. J Med Chem. 2021 Jul 22. 64 (14),10019-10026頁 (共著) 2021/07
論文
Suppression of IgE-independent degranulation of murine connective tissue-type mast cells by dexamethasone Cells, 112; https://doi.org/10.3390/cells8020112 8 (2) (共著) 2019/03
論文
1O, 20O-diacetyl kamebakaurin protects against acetaminophen-induced hepatotoxicity in mice Biomedical Research (Tokyo), 2018 39 (5),251-260頁 (共著) 2018/10
論文
Suppressive effect of kamebakaurin on acetaminophen-induced hepatotoxicity by inhibiting lipid peroxidation and inflammatory response in mice. Pharmacol Rep. 2017 69 (5),903-907頁 (共著) 2017/04
論文
Vitamin D3-induced hypercalcemia increases carbon tetrachloride-induced hepatotoxicity through elevated oxidative stress in mice. PLoS One. 2017 :e017652 12 (4) (共著) 2017/04
論文
Chronotoxicity of bromobenzene-induced hepatic injury in mice J Toxicol Sci. 2017 42 (2),251-258頁 (共著) 2017/01
論文
Bromobenzene-induced lethal toxicity in mouse is prevented by pretreatment with zinc sulfate. Chem Biol Interact. 2016 Jul 25;117-23. 254 (共著) 2016/07
論文
Calcium-deficient diet attenuates carbon tetrachloride-induced hepatotoxicity in mice through suppression of lipid peroxidation and inflammatory response. Heliyon. 2016 Jun 24 2 (6) (共著) 2016/06
論文
Carbon Tetrachloride-Induced Nephrotoxicity in Mice Is Prevented by Pretreatment with Zinc Sulfate. Biol Pharm Bull. 2016;1042-6. 39 (6) (共著) 2016/06
論文
Compound 48/80, a mast cell stimulator, enhances synthesis of IgE and IgG induced by intranasal application of ovalbumin in mice Biol Pharm Bull. 2015;1954-9. 38 (12) (共著) 2015/12
論文
CD72 negatively regulates mouse mast cell functions and down-regulates the expression of KIT and FcεRIα. Int Immunol. 2015 Feb;doi: 10.1093/intimm/dxu087. Epub 2014 Sep 19 27 (2),95-103頁 (共著) 2015/02
論文
Nonpeptide neurotrophic agents useful in the treatment of nertodegenerative diseases such as Alzheimer's disease J Pharmacol Sci. 2015 Feb 127 (2),155-163頁 (共著) 2015/02
論文
Does β-Hexosaminidase Function Only as a Degranulation Indicator in Mast Cells? The Primary Role of β-Hexosaminidase in Mast Cell Granules. J Immunol.15;1886-94. 193 (4) (共著) 2014/08
論文
Generation of mast cells from mouse fetus: analysis of differentiation and functionality, and transcriptome profiling using next generation sequencer. PLoS One. 2013:e60837. doi: 10.1371/journal.pone.0060837. Epub 2013 Apr 3 8 (4) (共著) 2013/04
論文
Phenylbutenoid dimers isolated from Zingiber purpureum exert neurotrophic effects on cultured neurons and enhance hippocampal neurogenesis in olfactory bulbectomized mice. Neurosci Lett. 2012 Mar 28;72-7 513 (1) (共著) 2012/03
論文
Mast cells modulate interleukin-4 production independently of interferon-gamma generation by invariant natural killer T cells through the suppression of Notch signaling Journal of Health Science. 2011 57 (2),197-203頁 (共著) 2011/04
論文
Human mast cells synthesize and release angiogenin, a member of the ribonuclease A (RNase A) superfamily. J Leukoc Biol. 2009 Nov;1217-26. 86 (5) (共著) 2009/11
論文
Lipoteichoic acid improves the capability of mast cells in the host defense system against bacteria Inflamm Res. 2009 Nov 58 (11),797-807頁 (共著) 2009/11
論文
Magnolol and honokiol prevent learning and memory impairment and cholinergic deficit in SAMP8 mice. Brain Res. 2009 Dec 11;108-17. 1305 (共著) 2009/11
論文
Inhibition of TNF-α production by heme oxygenase-1 (HO-1) on activated mast cells. World Allegy Organization Journal. 9-11 (共著) 2009/10
論文
Human cathelicidin CAP18/LL-37 changes mast cell function toward innate immunity. Biol Pharm Bull:212-6 31 (2) (共著) 2008/02
論文
Lipoteichoic acid downregulates FcepsilonRI expression on human mast cells through Toll-like receptor 2. J Allergy Clin Immunol. 2007 Aug 120,452-461頁 (共著) 2007/08
論文
Heme oxygenase-1 inhibits cytokine production by activated mast cells. Biochem Biophys Res Commun (共著) 2007/03
論文
Upregulation of heme oxygenase-1 by degranulation in rat basophilic leukemia cells. Biol Pharm Bull:443-6 30 (3) (共著) 2007/03
論文
Bacterial Components Regulate the Expression of Toll-like receptor 4 on Human Mast Cells. Inflamm.Res. 56,70-75頁 (共著) 2006/02
論文
Mast cells, which interact with Escherichia coli, up-regulate genes associated with innate immunity and become less responsive to Fc{epsilon}RI-mediated activation. J Leukoc Biol. 79,339-350頁 (共著) 2006/02
論文
The protective effect of H2-receptor activation against the duration of myocardial hypoxia/reoxygenation-induced ventricular fibrillation in sensitized guinea-pig hearts. Pharmacol Sci. 99,400-407頁 (共著) 2005/12
論文
Enzymatic measurement of tryptase-like protease release from isolated perfused guinea pig heart during ischemia-reperfusion. Biol Pharm Bull. 28,2149-2151頁 (共著) 2005/11
論文
Neurotrophic effect of magnolol in the hippocampal CA1 region of senescence-accelerated mice (SAMP1). Biol Pharm Bull. 28,1762-1765頁 (共著) 2005/09
論文
Protective effect of the 5-lipoxygenase inhibitor ardisiaquinone A on hepatic ischemia-reperfusion injury in rats. Planta Med. 71,717-720頁 (共著) 2005/08
論文
Inhibition of NF-kB activation during ischemia reduces hepatic ischemia-reperfusion injury in rats. J Pharmacol Sci. 30,103-110頁 (共著) 2005/05
論文
The role of mast cells in allergic inflammation--from the view point of innate immune system involvement. Foria Pharmacologica Japonica. 125,259-264頁 (共著) 2005/05
論文
Sounding the alarm in infection; Mast cells counter-attack. Allergy Clin Immunol Int. 16,1-5頁 (共著) 2004/02
論文
Identification of Fyn-binding proteins in MC/9 mast cells using mass spectrometry. Biochem Biophys Res Commun. 310 (1),202-208頁 (共著) 2003/10
論文
Involvement of arachidonic acid in nonimmunologic production of superoxide in mast cells. Int Arch Allergy Immunol. 130 (4),288-299頁 (共著) 2003/04
論文
Inhibitory effect of olopatadine on antigen-induced eosinophil infiltration and the LFA-1 and Mac-1 expression in eosinophils. Jpn J Pharmacol. 88 (4),463-466頁 (共著) 2002/04
論文
Antiallergic effect of ardisiaquinone A, a potent 5-lipoxygenase inhibitor. Phytomedicine. 8 (6),460-464頁 (共著) 2001/11
論文
Roles of superoxide dismutase in rat mast cell granules. Int Arch Allergy Immunol. 126 (2),140-146頁 (共著) 2001/10
論文
Inhibitory effect of KW-4679 on the infiltration of eosinophils in the nasal mucosa of rat allergic rhinitis models. Jpn Pharmacol Ther. 29 (3),187-191頁 (共著) 2001/08
論文
Xanthine oxidase-derived reactive oxygen species activate nuclear factor kappa B during hepatic ischemia in rats. Jpn J Pharmacol. 84 (3),363-366頁 (共著) 2000/11
論文
ラット肝虚血-再灌流モデルにおけるNF-κBの活性化 腎とフリーラジカル 5,51-54頁 (共著) 2000/09
論文
Novel action of quinolones on osteoclast-like cells. J Toxicol Sci. 24 (5),383-391頁 (共著) 1999/12
論文
Role of superoxide generation and degradation system of mast cells in allergic inflammation. Foria Pharmacol. Jpn. 112,73-77頁 (共著) 1998/10
論文
Inhibitor effect of apafant on bronchopulmonary responses to platelet activating factor and to antigen in rats. Arzneimittelforschung 47 (12),1364-1369頁 (共著) 1997/12
論文
The mechanisms of compound 48/80-induced superoxide generation mediated by A-kinase in rat peritoneal mast cells. Biochem Mol Med. 61 (1),107-113頁 (共著) 1997/07
論文
Anti-allergic effect of tea-leaf saponin (TLS) from tea leaves (Camellia sinensis var. sinensis). Biol Pharm Bull. 20 (5),565-567頁 (共著) 1997/05
論文
活性酸素産生系を標的とした抗アレルギー薬の評価 Foria Pharmacol. Jpn. 108,161-166頁 (共著) 1996/07
論文
Role of histamine H3 receptor on hypoxia-reoxygenation-induced cardiac dysfunction in guinea pigs. Methods Find Exp Clin Pharmacol. 17,30-35頁 (共著) 1995/11
論文
制癌剤シスプラチンによる培養腎上皮細胞株での過酸化脂質増大 Lipid Peroxide Research 19,113-114頁 (共著) 1995/10
論文
Inhibitory effect of epinastine on superoxide generation by rat neutrophils. Jpn J Pharmacol. 68 (4),449-452頁 (共著) 1995/08
論文
タンニンの活性酸素によるラット腹腔肥満細胞からのヒスタミン遊離に対する抑制効果 Folia Pharmacol. Jpn. 106,207-211頁 (共著) 1995/06
論文
Contribution of platelet activating factor (PAF) in histamine-induced model of nasal allergy in rats. pn. J. Allergol. 44,182-188頁 (共著) 1995/05
論文
Superoxide anion-induced histamine release from rat peritoneal mast cells. Biol Pharm Bull. 17 (5),732-734頁 (共著) 1994/05
論文
Amelioration by ascorbic acid of cisplatin-induced injury in cultured renal epithelial cells. Contrib Nephrol:138-42. 95 (共著) 1991/05
論文
In vitro nephrotoxicity test of platinum (II) antitumor agents using renal cells in culture. Eur. J. Pharmacol. 183,231-232頁 (共著) 1990/08
論文
Use of cultured renal epithelial cells for the study of cisplatin toxicity. Jpn J Pharmacol. 50 (2),247-249頁 (共著) 1989/06
論文
Glutathione depletion in rat kidney cortical slices: Its relation to cisplatin-induced lipid peroxidation. Medical Biochemical and Chemical Aspects of Free Radicals,563-566頁 (共著) 1988/08
論文
Effect of N-N'-diphenyl-p-phenylenediamine pretreatment on urinary enzyme excretion in cisplatin nephrotoxicity in rats. Jpn J Pharmacol 46 (1),90-92頁 (共著) 1988/01
論文
Stimulatory effect of cisplatin on production of lipid peroxidation in renal tissues. Jpn J Pharmacol 43 (3),247-252頁 (共著) 1987/03
その他
日本薬理学雑誌 Vol. 125, 259-264. 日本薬理学雑誌 125,259-264頁 (共著) 2005/05
その他
アレルギーと神経ペプチド アレルギーと神経ペプチド (単著) 2005/03
その他
J World Allergy Org. 7: 7-12 J World Allergy Org. 7,7-12頁 (共著) 2004/09
その他
学位論文 (単著) 1997/03
その他
特許 (共著) 1996/01
閉じる