学術研究データベース - 山口智広

ヤマグチ　トモヒロ YAMAGUCHI Tomohiro
山口智広

所属金城学院大学薬学部薬学科

職種教授

著書・論文歴
著書	分子糖尿病学の進歩―基礎から応用まで―2008 (共著) 2008/04
論文	Methyl dehydroabietate counters high fat diet-induced insulin resistance and hepatic steatosis by modulating peroxisome proliferator-activated receptor signaling in mice. Biomed Pharmacother 99,214-219頁 (共著) 2018/03
論文	Perilipins: a diversity of intracellular lipid droplet proteins. Lipids Health Dis.83 16 (共著) 2017/04
論文	Characterization of lipid droplets in steroidogenic MLTC-1 Leydig cells: Protein profiles and the morphological change induced by hormone stimulation. Biochim. Biophys. Acta. 467,906-912頁 (共著) 2015/10
論文	Olanzapine promotes the accumulation of lipid droplets and the expression of multiple perilipins in human adipocytes. Biochem Biophys Res Commun. 467,906-912頁 (共著) 2015/10
論文	Time course-changes in phosphatidylcholine profile during oxidative modification of low-density lipoprotein. Lipids Health Dis. 48 13 (共著) 2014/03
論文	Crucial role of Perilipin-3 (TIP47) in formation of lipid droplets and PGE2 production in HL-60-derived neutrophils. PLoS One.e71542 8 (共著) 2013/08
論文	Active involvement of micro-lipid droplets and lipid droplet-associated proteins in hormone-stimulated lipolysis in adipocytes. J Cell Sci. 125,6127-6136頁 (共著) 2012/12
論文	Perilipin 5, a lipid droplet-binding protein, protects heart from oxidative burden by sequestering fatty acid from excessive oxidation. J Biol Chem. 287,23852-23863頁 (共著) 2012/07
論文	Oxidized low-density lipoprotein-induced periodontal inflammation is associated with the up-regulation of cyclooxygenase-2 and microsomal prostaglandin synthase 1 in human gingival epithelial cells. Biochem Biophys Res Commun. 413,566-571頁 (共著) 2011/10
論文	Dietary cholesterol reduces plasma triacylglycerol in apolipoprotein E-null mice: suppression of lipin-1 and -2 in the glycerol-3-phosphate pathway. PLoS One.e22917 6 (共著) 2011/08
論文	Unique regulation of adipose triglyceride lipase (ATGL) by perilipin 5, a lipid droplet-associated protein. J Biol Chem. 286,15707-15715頁 (共著) 2011/05
論文	Glucagon regulates intracellular distribution of adipose differentiation-related protein during triacylglycerol accumulation in the liver. J. Lipid Res. 51,2571-2580頁 (共著) 2010/09
論文	Crucial role of CGI-58/α/β hydrolase domain-containing protein 5 in lipid metabolism. Biol Pharm Bull. 33,342-345頁 (単著) 2010/03
論文	Activation of hormone-sensitive lipase requires two steps, protein phosphorylation and binding to the PAT-1 domain of lipid droplet coat proteins. J. Biol. Chem. 284,32116-32125頁 (共著) 2009/11
論文	Chanarin-Dorfman syndrome: deficiency in CGI-58, a lipid droplet-bound coactivator of lipase. Biochim Biophys Acta. 1791,519-523頁 (共著) 2009/06
論文	FSP27 contributes to efficient energy storage in murine white adipocytes by promoting the formation of unilocular lipid droplets. J. Clin. Invest. 118,2808-2821頁 (共著) 2008/08
論文	Perilipin, a critical regulator of fat storage and breakdown, is a target gene of estrogen receptor-related receptor α. Biochem. Biophys. Res. Commun. 368,563-568頁 (共著) 2008/04
論文	細胞内の脂肪滴表面における中性脂肪の代謝機構表面 46,178-191頁 (単著) 2008/04
論文	脂肪分解におけるPerilipinの展開 The Lipid 19,35-41頁 (共著) 2008/01
論文	CGI-58 facilitates lipolysis on lipid droplets but is not involved in the vesiculation of lipid droplets caused by hormonal stimulation. J. Lipid Res. 48,1078-1089頁 (共著) 2007/05
論文	hDREF regulates cell proliferation and expression of ribosomal protein genes. Mol. Cell. Biol. 27,2003-2013頁 (共著) 2007/03
論文	hDREF self-association via hATC domain is necessary for its nuclear accumulation and DNA binding. J. Biol. Chem. 282,7563-7575頁 (共著) 2007/03
論文	Orphan nuclear receptor Nur77 accelerates the initial phase of adipocyte differentiation in 3T3-L1 cells by promoting mitotic clonal expansion. J. Biochem. 141,181-192頁 (共著) 2007/02
論文	脂肪滴での脂肪分解と蓄積を制御するPATファミリー生化学 79,162-166頁 (単著) 2007/02
論文	Identification of a gene sharing a promoter and peroxisome proliferator-response elements with acyl-CoA oxidase gene. PPAR Research, Article ID 71916, 10 2006 (共著) 2006/09
論文	Aspects of the regulatory mechanisms of PPAR functions: analysis of a bidirectional response element and regulation by sumoylation. Mol. Cell. Biochem. 286,33-42頁 (共著) 2006/06
論文	Analysis of interaction partners for perilipin and ADRP on lipid droplets. Mol. Cell. Biochem. 284,167-173頁 (共著) 2006/03
論文	MLDP, a novel PAT family protein localized to lipid droplets and enriched in the heart, is regulated by peroxisome proliferator-activated receptor-α. J. Biol. Chem. 281,14232-14240頁 (共著) 2006/03
論文	Peroxisome proliferator-activated receptor subtypes differentially cooperate with other transcription factors in selective transactivation of the perilipin/ PEX11α gene pair. J. Biochem. 139,563-573頁 (共著) 2006/03
論文	Negative regulation of adipogenesis from human mesenchymal stem cells by Jun N-terminal kinase. Biochem. Biophys. Res. Commun. 326,499-504頁 (共著) 2005/01
論文	The transactivating function of peroxisome proliferator-activated receptor-γ is negatively regulated by SUMO conjugation in the amino-terminal domain. Genes to Cells 9,1017-1029頁 (共著) 2004/11
論文	CGI-58 interacts with perilipin and is localized to lipid droplets: Possible involvement of CGI-58 mislocalization in Chanarin-Dorfman syndrome. J. Biol. Chem. 279,30490-30497頁 (共著) 2004/07
論文	SKIP modifies gene expression by affecting both transcription and splicing. Biochem. Biophys. Res. Commun. 316,512-517頁 (共著) 2004/04
論文	Convergence and divergence in the mechanism of SNARE binding by Sec1/Munc18- like proteins. Proc. Natl. Acad. Sci. USA. 100,32-37頁 (共著) 2003/01
論文	Inactivation of Gαz causes disassembly of the Golgi apparatus. J. Cell Sci. 115,4483-4493頁 (共著) 2002/12
論文	How Tlg2p/syntaxin 16 'Snares' Vps45. EMBO J. 21,3620-3631頁 (共著) 2002/07
論文	Sly1 binds to Golgi and ER Syntaxins via a conserved N-terminal peptide motif. Dev. Cell 2,295-305頁 (共著) 2002/03
論文	Vam3p structure reveals conserved and divergent properties of Syntaxins. Nat. Struct. Biol. 8,258-264頁 (共著) 2001/03
論文	Regulation of the Golgi structure by the α subunits of heterotrimeric G proteins. FEBS Letters. 470,25-28頁 (共著) 2000/03
論文	ADP-ribosylation factor-1 is sensitive to N-ethylmaleimide. J. Biochem. 124,1229-1236頁 (共著) 1998/12
論文	Possible involvement of heterotrimeric G proteins in the organization of the Golgi apparatus. J. Biol. Chem. 272,25260-25266頁 (共著) 1997/10